Yixiang Deng

Yixiang Deng

Assistant Professor at the University of Delaware

Publications

Preprints

  1. Y. Deng, K. Arao, C. Mantzoros, G. Karniadakis. Patient-specific deep offline artificial pancreas for blood glucose regulation in type 1 diabetes. bioRxiv, 2022.

  2. M. Agraz*, Y. Deng*, G. Karniadakis, C. Mantzoros. Long-term Prediction of Severe Hypoglycemia in Type 2 Diabetes Based on Multi-view Co-training. medRxiv, 2023.

Journal Papers during Postdoc

  1. Y. Deng*; M. Tang*; T. M. Ross; A. G. Schmidt; A. K. Chakraborty; D. Lingwood. [Repeated vaccination with homologous influenza hemagglutinin broadens human antibody responses to unmatched flu viruses]. submitted, 2024.

  2. N. Nziza*, Y. Deng*, L. Wood, N. Dhanoa, N. Dulit-Greenberg, T. Chen, A. Kane, Z. Swank, J. Davis, M. Demokritou, A. P. Chitnis, A. Fasano, A. G. Edlow, N. Jain, B. Horwitz, R. McNamara, B. Julg, W. G. Shreffler, G. Alter, L. M. Yonker Humoral profiles of toddlers and young children following SARS-CoV-2 mRNA vaccination. Nature Communications, 2024.

  3. X. Tong*, Y. Deng*, D. Cizmeci, L. Fontana, M. A. Carlock, H. B. Hanley, R. P. McNamara, D. Lingwood, T. M. Ross, G. Alter. Distinct Functional Humoral Immune Responses Are Induced after Live Attenuated and Inactivated Seasonal Influenza Vaccination. Journal of Immunology, 2024 (Cover Article).

  4. Y. Deng*, C. Atyeo, D. Yuan, T. M Chicz, T. Tibbitts, M. Gorman, S. Taylor, V. Lecouturier, D. A. Lauffenburger, R. M. Chicz, G. Alter, R. P. McNamara Beta-spike-containing boosters induce robust and functional antibody responses to SARS-CoV-2 in macaques primed with distinct vaccines. Cell Reports, 2023.

  5. P. Kaplonek*, Y. Deng*, J. Lee, H. Zar, D. Zavadska, M. Johnson, D. A. Lauffenburger, D. Goldblatt, G. Alter. Hybrid immunity expands the functional humoral footprint of both mRNA and vector-based SARS-CoV-2 vaccines. Cell Reports Medicine, 2023.

  6. M. Spatola, N.e Nziza, W. Jung, Y. Deng, D. Yuan, A. Dinoto, S. Bozzetti, V. Chiodega, S. Ferrari, D. A. Lauffenburger, S. Mariotto, G. Alter. Neurologic sequelae of COVID-19 are determined by immunologic imprinting from previous coronaviruses. Brain, 2023.

  7. C. Berry, V. Pavot, N. G. Anosova, M. Kishko, L. Li, T. Tibbitts, A. Raillard, S. Gautheron, S. Cummings, D. S. Bangari, S. Kar, C. Atyeo, Y. Deng, G. Alter, C. Gutzeit, M. Koutsoukos, R. M Chicz, V. Lecouturier. Beta-containing bivalent SARS-CoV-2 protein vaccine elicits durable broad neutralization in macaques and protection in hamsters. Communications Medicine, 2023.

Journal Papers before Postdoc

  1. Y. Deng+, H. Li+. Deep learning for few-shot white blood cell image classification and feature learning. Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization, 2023.

  2. M. Kouvari, L. Valenzuela-Vallejo, V. Guatibonza-Garcia, S. A. Polyzos, Y. Deng, …, C. S. Mantzoros. Liver biopsy-based validation, confirmation and comparison of the diagnostic performance of established and novel non-invasive steatotic liver disease indexes: Results from a large multi-center study. Metabolism, 2023

  3. Q. Zhang, K. Sampani, M. Xu, S. Cai, Y. Deng, H. Li, J. K. Sun, G. Karniadakis. AOSLO-net: A deep learning-based method for automatic segmentation of retinal microaneurysms from adaptive optics scanning laser ophthalmoscope images. Translational Vision Science & Technology, 11(8), 7-7, 2022

  4. H. Li*, Y. Deng*, Z. Li, A. D. Gallastegi, C. Mantzoros, G. H. Frydman, G. Karniadakis. Multi-physics and multiscale modeling of microthrombosis in COVID-19. PLOS Computational Biology, 18(3), e1009892, 2022

  5. Y. Deng, H. Chang, H. Li. Recent Advances in Computational Modeling of Biomechanics and Biorheology of Red Blood Cells in Diabetes. Biomimetics 7(1), 15, 2022.

  6. H. Li, Y. Deng, K. Sampani, S. Cai, Z. Li, J. Sun, G. Karniadakis. Computational investigation of blood cell transport in retinal microaneurysms. PLOS Computational Biology, 18(1), e1009728, 2022.

  7. Y. Deng*, L. Lu*, L. Aponte, A. M. Angelidi, V. Novak, G. Karniadakis, C. Mantzoros. Deep transfer learning and data augmentation improve glucose levels prediction in type 2 diabetes patients. npj Digital Medicine, 4, 109, 2021. [code]

  8. E. Javadi, Y. Deng, G. Karniadakis, S. Jamali. In silico biophysics and hemorheology of blood hyperviscosity syndrome. Biophysical Journal, 120(13):2723-33, 2021.

  9. A. Yazdani*, Y. Deng*, H. Li*, E. Javadi, Z. Li, S. Jamali, J. Humphrey, C. Mantzoros, G. Karniadakis. Integration of blood cell mechanics and platelet adhesive dynamics with coagulation cascade: application to normal and diabetic blood. Journal of Royal Society Interface, 18(175), 20200834, 2021. [code]

  10. Y. Deng, G. Lin, X. Yang. Multifidelity data fusion via gradient-Enhanced gaussian process regression. Communications in Computational Physics, 28(5), 1812–1837, 2020.

  11. Y. Deng*, D. Papageorgiou*, X. Li, N. Perakakis, C. S. Mantzoros, M. Dao, G. Karniadakis. Quantifying fibrinogen-Dependent aggregation of red blood cells in type 2 diabetes mellitus. Biophysical Journal, 119(5), 900–912, 2020.

  12. Y. Deng*, D. Papageorgiou*, H. Chang, S. Abidi, X. Li, M. Dao, G. Karniadakis. Quantifying shear-induced deformation and detachment of individual adherent sickle red blood cells. Biophysical Journal, 116(2), 360–371, 2019.

  13. H. Li, D. Papageorgiou, H. Y. Chang, L. Lu, J. Yang, Y. Deng. Synergistic integration of laboratory and numerical approaches in studies of the biomechanics of diseased red blood cells. Biosensors, 8(3), 76, 2018.

  14. L. Lu*, Y. Deng*, X. Li, H. Li, G. Karniadakis. Understanding the twisted structure of amyloid fibrils via molecular simulations. The Journal of Physical Chemistry B, 122(49), 11302–11310, 2018.